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Microtome cutting
There are many types of microtomes available on the market, and it can be difficult to choose the right one for your lab. Before making a purchase, though, it is essential to conduct proper research. The Laboratory App has compiled important microtome information to help you find the right tool for your application. It also offers questions to help you match the best microtome for your lab with the right safety features, quality sections, and maintenance services.
One type of microtome is the saw-based microtome, which requires a rotating saw to cut materials up to thirty micrometers thick. Alternatively, you can opt for a laser-cut microtome, which allows non-contact cutting and slices tissues up to 100 micrometers thick. A saw-based microtome will require more force when cutting, but is generally better suited for thin materials. Regardless of which type you choose, though, there are many advantages and disadvantages to choosing the right microtome.
A microtome is often used to produce frozen sections for microscopic analysis. This is different from histology, which uses a microscope to slice and analyze tissue. The process of cryosectioning focuses on studying tissue in its native state. This method allows scientists to study specimens that are close to their natural state without undergoing extensive treatment. And the benefits are numerous. These tools can save time and improve patient care. The following are just some of the advantages of microtomes.
The two most common types of microtomes are vibrating and ultra-vibrating. The first two types use a blade to slice through specimens. The latter uses vibration instead of pressure, reducing mechanical forces on the samples. This type is usually used for difficult biological samples, as it reduces the mechanical force on the tissues and ensures that all viable cells are preserved. The third type is the infrared laser microtome, which is another type of microscope. The lasers work by imparting IR energy onto a sample. It provides precision and control, and it does not decalcify the samples. Despite this technology, the speed is slow and the accuracy of 1um are far from sufficient for routine pathology applications.
The Microtome has many advantages over conventional cutting methods. Unlike the latter, which require manual preparation, microtomes allow scientists to prepare samples with a very thin thickness. These microtomes can slice tissues as thin as 10 nm. Therefore, they are a popular option for routine use in clinical laboratories. These machines are specialized for cutting large blocks of tissue. These devices are also incredibly stable and are very convenient to use.
The two most common types of microtomes are manual and semi-automatic. The former is more manual, and uses a handwheel to maneuver the specimen feed. The latter is the more expensive option, but it is better suited to sensitive tissues. It costs less than the manual version. It has the most advantages and disadvantages, but it is more ergonomic. Its advantages over the semi-automated version include more precision and safety.